Mechanisms for Vascular Cell Adhesion Molecule-1 Activation of ERK1/2 during Leukocyte Transendothelial Migration

BACKGROUND: During inflammation, adhesion molecules regulate recruitment of leukocytes to inflamed tissues. It is reported that vascular cell adhesion molecule-1 (VCAM-1) activates extracellular regulated kinases 1 and 2 (ERK1/2), but the mechanism for this activation is not known. Pharmacological i...

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Bibliographic Details
Main Authors: Abdala-Valencia, Hiam, Berdnikovs, Sergejs, Cook-Mills, Joan M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198778/
https://ncbi.nlm.nih.gov/pubmed/22031842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026706
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