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Distinct Sites within the VCAM-1 Cytoplasmic Domain Regulate VCAM-1 Activation of Calcium Fluxes versus Rac1 during Leukocyte Transendothelial Migration

Vascular adhesion molecules regulate the migration of leukocytes from the blood into tissue during inflammation. Leukocyte binding to vascular cell adhesion molecule-1 (VCAM-1) activates signals in endothelial cells, including Rac1 and calcium fluxes. These VCAM-1 signals are required for leukocyte...

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Sonraí Bibleagrafaíochta
Main Authors: Marchese, Michelle E., Berdnikovs, Sergejs, Cook-Mills, Joan M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558628/
https://ncbi.nlm.nih.gov/pubmed/22970700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300925r
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