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Distinct Sites within the VCAM-1 Cytoplasmic Domain Regulate VCAM-1 Activation of Calcium Fluxes versus Rac1 during Leukocyte Transendothelial Migration

Vascular adhesion molecules regulate the migration of leukocytes from the blood into tissue during inflammation. Leukocyte binding to vascular cell adhesion molecule-1 (VCAM-1) activates signals in endothelial cells, including Rac1 and calcium fluxes. These VCAM-1 signals are required for leukocyte...

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Auteurs principaux: Marchese, Michelle E., Berdnikovs, Sergejs, Cook-Mills, Joan M.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558628/
https://ncbi.nlm.nih.gov/pubmed/22970700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300925r
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