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PTP1B deficiency exacerbates inflammation and accelerates leukocyte trafficking in vivo
It is reported that PTP1B limits cytokine signaling in vitro. However, PTP1B’s function during inflammation in vivo is not known. In this report, we determined whether PTP1B deficiency affects allergic inflammation in vivo. Briefly, lungs of OVA-challenged PTP1B−/− mice had elevated numbers of eosin...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3253258/ https://ncbi.nlm.nih.gov/pubmed/22156494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1004108 |
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