PTP1B deficiency exacerbates inflammation and accelerates leukocyte trafficking in vivo

It is reported that PTP1B limits cytokine signaling in vitro. However, PTP1B’s function during inflammation in vivo is not known. In this report, we determined whether PTP1B deficiency affects allergic inflammation in vivo. Briefly, lungs of OVA-challenged PTP1B−/− mice had elevated numbers of eosin...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Berdnikovs, Sergejs, Pavlov, Vladimir I., Abdala-Valencia, Hiam, McCary, Christine A., Klumpp, David J., Tremblay, Michel L., Cook-Mills, Joan M.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253258/
https://ncbi.nlm.nih.gov/pubmed/22156494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1004108
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker