Highly Efficient Generation of Transgenic Sheep by Lentivirus Accompanying the Alteration of Methylation Status

BACKGROUND: Low efficiency of gene transfer and silence of transgene expression are the critical factors hampering the development of transgenic livestock. Recently, transfer of recombinant lentivirus has been demonstrated to be an efficient transgene delivery method in various animals. However, the...

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Autori principali: Liu, Chenxi, Wang, Liqin, Li, Wenrong, Zhang, Xuemei, Tian, Yongzhi, Zhang, Ning, He, Sangang, Chen, Tong, Huang, Juncheng, Liu, Mingjun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558511/
https://ncbi.nlm.nih.gov/pubmed/23382924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054614
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