Highly Efficient Generation of Transgenic Sheep by Lentivirus Accompanying the Alteration of Methylation Status

BACKGROUND: Low efficiency of gene transfer and silence of transgene expression are the critical factors hampering the development of transgenic livestock. Recently, transfer of recombinant lentivirus has been demonstrated to be an efficient transgene delivery method in various animals. However, the...

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Autors principals: Liu, Chenxi, Wang, Liqin, Li, Wenrong, Zhang, Xuemei, Tian, Yongzhi, Zhang, Ning, He, Sangang, Chen, Tong, Huang, Juncheng, Liu, Mingjun
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558511/
https://ncbi.nlm.nih.gov/pubmed/23382924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054614
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