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Participation of the Ubiquitin-Conjugating Enzyme UBE2E3 in Nedd4-2-Dependent Regulation of the Epithelial Na(+) Channel
The epithelial Na(+) channel (ENaC) is a heteromeric protein complex playing a fundamental role in Na(+) homeostasis and blood pressure regulation. Specific mutations inactivating PY motifs in ENaC C termini cause Liddle's syndrome, an inherited form of hypertension. Previously we showed that t...
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| Glavni autori: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2004
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC355826/ https://ncbi.nlm.nih.gov/pubmed/14993279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.6.2397-2409.2004 |
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