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Conformational Dynamics Modulate Activation of the Ubiquitin Conjugating Enzyme Ube2g2
[Image: see text] The ubiquitin conjugating enzyme Ube2g2 together with its cognate E3 ligase gp78 catalyzes the synthesis of lysine-48 polyubiquitin chains constituting signals for the proteasomal degradation of misfolded proteins in the endoplasmic reticulum. Here, we employ NMR spectroscopy in co...
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| Publicado no: | ACS Omega |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2017
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5579538/ https://ncbi.nlm.nih.gov/pubmed/28884161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00205 |
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