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Sequence Recombination Improves Target Specificity in a Redesigned Collagen Peptide abc-type Heterotrimer

Stability of the collagen triple helix is largely governed by its imino acid content, namely the occurrence of proline and 4R-hydroxyproline at the X and Y positions respectively of the periodic (Gly-X-Y)(n) sequence. Although other amino acids at these positions reduce stability of the triple helix...

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Autori principali: Giddu, Sumana, Xu, Fei, Nanda, Vikas
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557756/
https://ncbi.nlm.nih.gov/pubmed/23042255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24194
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