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Sequence Recombination Improves Target Specificity in a Redesigned Collagen Peptide abc-type Heterotrimer
Stability of the collagen triple helix is largely governed by its imino acid content, namely the occurrence of proline and 4R-hydroxyproline at the X and Y positions respectively of the periodic (Gly-X-Y)(n) sequence. Although other amino acids at these positions reduce stability of the triple helix...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3557756/ https://ncbi.nlm.nih.gov/pubmed/23042255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24194 |
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