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Computational Design of a Collagen A:B:C-type Heterotrimer
We have successfully designed an A:B:C collagen peptide heterotrimer using an automated computational approach. The algorithm maximizes the energy gap between the target and competing misfolded states while enforcing a minimum target stability. Circular dichroism (CD) measurements confirm that all t...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3443875/ https://ncbi.nlm.nih.gov/pubmed/21902217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja205597g |
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