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De Novo Self-Assembling Collagen Heterotrimers using Explicit Positive and Negative Design

We sought to computationally design model collagen peptides that specifically associate as heterotrimers. Computational design has been successfully applied to the creation of new protein folds and functions. Despite the high abundance of collagen and its key role in numerous biological processes, f...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Xu, Fei, Zhang, Lei, Koder, Ronald L., Nanda, Vikas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853261/
https://ncbi.nlm.nih.gov/pubmed/20170197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902077d
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