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De Novo Self-Assembling Collagen Heterotrimers using Explicit Positive and Negative Design
We sought to computationally design model collagen peptides that specifically associate as heterotrimers. Computational design has been successfully applied to the creation of new protein folds and functions. Despite the high abundance of collagen and its key role in numerous biological processes, f...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2853261/ https://ncbi.nlm.nih.gov/pubmed/20170197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902077d |
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