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Control of Collagen Stability and Heterotrimer Specificity through Repulsive Electrostatic Interactions

Charge-pair interactions between acidic and basic residues on the surface of collagen can promote stability as well as control specificity of molecular recognition. Heterotrimeric collagen peptides have been engineered de novo using either rational or computational methods, which in both cases optim...

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Detalhes bibliográficos
Main Authors: Parmar, Avanish S., Joshi, Mihir, Nosker, Patrick L., Hasan, Nida F., Nanda, Vikas
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030969/
https://ncbi.nlm.nih.gov/pubmed/24970200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom3040986
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