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Biological and Therapeutic Relevance of Nonreplicative DNA Polymerases to Cancer

Apart from surgical approaches, the treatment of cancer remains largely underpinned by radiotherapy and pharmacological agents that cause damage to cellular DNA, which ultimately causes cancer cell death. DNA polymerases, which are involved in the repair of cellular DNA damage, are therefore potenti...

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Detalhes bibliográficos
Main Authors: Parsons, Jason L., Nicolay, Nils H., Sharma, Ricky A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557440/
https://ncbi.nlm.nih.gov/pubmed/22794079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2011.4203
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