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Biological and Therapeutic Relevance of Nonreplicative DNA Polymerases to Cancer

Apart from surgical approaches, the treatment of cancer remains largely underpinned by radiotherapy and pharmacological agents that cause damage to cellular DNA, which ultimately causes cancer cell death. DNA polymerases, which are involved in the repair of cellular DNA damage, are therefore potenti...

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Bibliografiske detaljer
Main Authors: Parsons, Jason L., Nicolay, Nils H., Sharma, Ricky A.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557440/
https://ncbi.nlm.nih.gov/pubmed/22794079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2011.4203
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