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Family A and B DNA Polymerases in Cancer: Opportunities for Therapeutic Interventions

DNA polymerases are essential for genome replication, DNA repair and translesion DNA synthesis (TLS). Broadly, these enzymes belong to two groups: replicative and non-replicative DNA polymerases. A considerable body of data suggests that both groups of DNA polymerases are associated with cancer. Man...

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Detalhes bibliográficos
Publicado no:Biology (Basel)
Main Authors: Shanbhag, Vinit, Sachdev, Shrikesh, Flores, Jacqueline A., Modak, Mukund J., Singh, Kamalendra
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872031/
https://ncbi.nlm.nih.gov/pubmed/29301327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology7010005
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