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WNT5A-NFAT Signaling Mediates Resistance to Apoptosis in Pancreatic Cancer

INTRODUCTION: WNT5A belongs to the Wnt family of secreted signaling molecules. Using transcriptional profiling, we previously identified WNT5A as target of the antiapoptotic transcription factor CUX1 and demonstrated high expression levels in pancreatic cancer. However, the impact of WNT5A on drug r...

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Bibliografiska uppgifter
Huvudupphovsmän: Griesmann, Heidi, Ripka, Stefanie, Pralle, Moritz, Ellenrieder, Volker, Baumgart, Sandra, Buchholz, Malte, Pilarsky, Christian, Aust, Daniela, Gress, Thomas M, Michl, Patrick
Materialtyp: Artigo
Språk:Inglês
Publicerad: Neoplasia Press Inc. 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556935/
https://ncbi.nlm.nih.gov/pubmed/23359789
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