WNT5A-NFAT Signaling Mediates Resistance to Apoptosis in Pancreatic Cancer

INTRODUCTION: WNT5A belongs to the Wnt family of secreted signaling molecules. Using transcriptional profiling, we previously identified WNT5A as target of the antiapoptotic transcription factor CUX1 and demonstrated high expression levels in pancreatic cancer. However, the impact of WNT5A on drug r...

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Autori principali: Griesmann, Heidi, Ripka, Stefanie, Pralle, Moritz, Ellenrieder, Volker, Baumgart, Sandra, Buchholz, Malte, Pilarsky, Christian, Aust, Daniela, Gress, Thomas M, Michl, Patrick
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press Inc. 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556935/
https://ncbi.nlm.nih.gov/pubmed/23359789
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