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Overexpression of c-myc in pancreatic cancer caused by ectopic activation of NFATc1 and the Ca(2+)/calcineurin signaling pathway

The nuclear factor of activated T cell (NFAT) proteins are a family of Ca(2+)/calcineurin-responsive transcription factors primarily recognized for their central roles in T lymphocyte activation and cardiac valve development. We demonstrate that NFATc1 is commonly overexpressed in pancreatic carcino...

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Main Authors: Buchholz, Malte, Schatz, Alexandra, Wagner, Martin, Michl, Patrick, Linhart, Thomas, Adler, Guido, Gress, Thomas M, Ellenrieder, Volker
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1538549/
https://ncbi.nlm.nih.gov/pubmed/16874304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601246
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