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Size-Exclusion Chromatography for the Analysis of Protein Biotherapeutics and their Aggregates

In recent years, the use and number of biotherapeutics has increased significantly. For these largely protein-based therapies, the quantitation of aggregates is of particular concern given their potential effect on efficacy and immunogenicity. This need has renewed interest in size-exclusion chromat...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Hong, Paula, Koza, Stephan, Bouvier, Edouard S. P.
פורמט: Artigo
שפה:Inglês
יצא לאור: Taylor & Francis 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556795/
https://ncbi.nlm.nih.gov/pubmed/23378719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10826076.2012.743724
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