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Inhibition of endoplasmic reticulum stress alleviates lipopolysaccharide-induced lung inflammation through modulation of NF-κB/HIF-1α signaling pathway

Lipopolysaccharide (LPS) is involved in a variety of inflammatory disorders. Under stress conditions, endoplasmic reticulum (ER) loses the homeostasis in its functions, which is defined as ER stress. Little is known how ER stress is implicated in LPS-induced lung inflammation. In this study, effects...

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Hlavní autoři: Kim, Hee Jung, Jeong, Jae Seok, Kim, So Ri, Park, Seung Yong, Chae, Han Jung, Lee, Yong Chul
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556596/
https://ncbi.nlm.nih.gov/pubmed/23359618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01142
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