Inhibition of endoplasmic reticulum stress alleviates lipopolysaccharide-induced lung inflammation through modulation of NF-κB/HIF-1α signaling pathway

Lipopolysaccharide (LPS) is involved in a variety of inflammatory disorders. Under stress conditions, endoplasmic reticulum (ER) loses the homeostasis in its functions, which is defined as ER stress. Little is known how ER stress is implicated in LPS-induced lung inflammation. In this study, effects...

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Autors principals: Kim, Hee Jung, Jeong, Jae Seok, Kim, So Ri, Park, Seung Yong, Chae, Han Jung, Lee, Yong Chul
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556596/
https://ncbi.nlm.nih.gov/pubmed/23359618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01142
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