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Inhibition of endoplasmic reticulum stress alleviates lipopolysaccharide-induced lung inflammation through modulation of NF-κB/HIF-1α signaling pathway

Lipopolysaccharide (LPS) is involved in a variety of inflammatory disorders. Under stress conditions, endoplasmic reticulum (ER) loses the homeostasis in its functions, which is defined as ER stress. Little is known how ER stress is implicated in LPS-induced lung inflammation. In this study, effects...

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Bibliografiske detaljer
Main Authors: Kim, Hee Jung, Jeong, Jae Seok, Kim, So Ri, Park, Seung Yong, Chae, Han Jung, Lee, Yong Chul
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556596/
https://ncbi.nlm.nih.gov/pubmed/23359618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01142
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