Inhibition of endoplasmic reticulum stress alleviates lipopolysaccharide-induced lung inflammation through modulation of NF-κB/HIF-1α signaling pathway

Lipopolysaccharide (LPS) is involved in a variety of inflammatory disorders. Under stress conditions, endoplasmic reticulum (ER) loses the homeostasis in its functions, which is defined as ER stress. Little is known how ER stress is implicated in LPS-induced lung inflammation. In this study, effects...

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Main Authors: Kim, Hee Jung, Jeong, Jae Seok, Kim, So Ri, Park, Seung Yong, Chae, Han Jung, Lee, Yong Chul
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556596/
https://ncbi.nlm.nih.gov/pubmed/23359618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01142
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