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Effect of Trastuzumab on Notch-1 Signaling Pathway in Breast Cancer SK-BR3 Cells

OBJECTIVE: To investigate the effects and mechanisms of trastuzumab on Notch-1 pathway in breast cancer cells, recognizing the significance of Notch-1 signaling pathway in trastuzumab resistance. METHODS: Immunocytochemistry staining and Western blotting were employed to justify the expression of No...

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Bibliografiske detaljer
Main Authors: Han, Ming, Deng, Hua-yu, Jiang, Rong
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag Berlin Heidelberg 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555277/
https://ncbi.nlm.nih.gov/pubmed/23358465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11670-012-0213-9
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