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Effect of Trastuzumab on Notch-1 Signaling Pathway in Breast Cancer SK-BR3 Cells
OBJECTIVE: To investigate the effects and mechanisms of trastuzumab on Notch-1 pathway in breast cancer cells, recognizing the significance of Notch-1 signaling pathway in trastuzumab resistance. METHODS: Immunocytochemistry staining and Western blotting were employed to justify the expression of No...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer-Verlag Berlin Heidelberg
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3555277/ https://ncbi.nlm.nih.gov/pubmed/23358465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11670-012-0213-9 |
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