8-Chloro-Adenosine Inhibits Proliferation of MDA-MB-231 and SK-BR-3 Breast Cancer Cells by Regulating ADAR1/p53 Signaling Pathway

8-Chloro-adenosine (8-Cl-Ado) has been shown to exhibit its antitumor activity by inducing apoptosis in human lung cancer A549 and H1299 cells or autophagy in chronic lymphocytic leukemia, and MDA-MB-231 and MCF-7 breast cancer cells. Adenosine deaminases acting on RNA 1 (ADAR1) is tightly associate...

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Detalhes bibliográficos
Publicado no:Cell Transplant
Main Authors: Ding, Hong-Yue, Yang, Wan-Yong, Zhang, Li-Hong, Li, Li, Xie, Feng, Li, Hua-Yi, Chen, Xiao-Yu, Tu, Zeng, Li, Yi, Chen, Yong, Yang, Sheng-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7784596/
https://ncbi.nlm.nih.gov/pubmed/32907379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0963689720958656
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