Enhanced Function of Redirected Human T Cells Expressing Linker for Activation of T Cells That Is Resistant to Ubiquitylation

It is likely that the enhancement of signaling after antigenic stimulation, particularly in the tumor microenvironment, would improve the function of adoptively transferred T cells. Linker for activation of T cells (LAT) plays a central role in T cell activation. We hypothesized that the ubiquitylat...

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Bibliografiska uppgifter
Huvudupphovsmän: Kunii, Naoki, Zhao, Yangbing, Jiang, Shuguang, Liu, Xiaojun, Scholler, John, Balagopalan, Lakshmi, Samelson, Lawrence E., Milone, Michael C., June, Carl H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Mary Ann Liebert, Inc. 2013
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555093/
https://ncbi.nlm.nih.gov/pubmed/22998346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2012.130
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