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The Fidelity of Transcription: RPB1 (RPO21) MUTATIONS THAT INCREASE TRANSCRIPTIONAL SLIPPAGE IN S. CEREVISIAE

The fidelity of RNA synthesis depends on both accurate template-mediated nucleotide selection and proper maintenance of register between template and RNA. Loss of register, or transcriptional slippage, is particularly likely on homopolymeric runs in the template. Transcriptional slippage can alter t...

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Main Authors: Strathern, Jeffrey, Malagon, Francisco, Irvin, Jordan, Gotte, Deanna, Shafer, Brenda, Kireeva, Maria, Lubkowska, Lucyna, Jin, Ding Jun, Kashlev, Mikhail
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2013
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554935/
https://ncbi.nlm.nih.gov/pubmed/23223234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.429506
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