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Polymer Uncrossing and Knotting in Protein Folding, and Their Role in Minimal Folding Pathways

We introduce a method for calculating the extent to which chain non-crossing is important in the most efficient, optimal trajectories or pathways for a protein to fold. This involves recording all unphysical crossing events of a ghost chain, and calculating the minimal uncrossing cost that would hav...

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Detalhes bibliográficos
Main Authors: Mohazab, Ali R., Plotkin, Steven S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554774/
https://ncbi.nlm.nih.gov/pubmed/23365638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053642
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