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Effects of Knots on Protein Folding Properties

This work explores the impact of knots, knot depth and motif of the threading terminus in protein folding properties (kinetics, thermodynamics and mechanism) via extensive Monte Carlo simulations of lattice models. A knotted backbone has no effect on protein thermodynamic stability but it may affect...

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Bibliografske podrobnosti
Main Authors: Soler, Miguel A., Faísca, Patrícia F. N.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762781/
https://ncbi.nlm.nih.gov/pubmed/24023962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074755
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