Učitavanje...

Cathepsin K Knockout Mitigates High-Fat Diet–Induced Cardiac Hypertrophy and Contractile Dysfunction

The cysteine protease cathepsin K has been implicated in pathogenesis of cardiovascular disease. We hypothesized that ablation of cathepsin K protects against obesity-associated cardiac dysfunction. Wild-type mice fed a high-fat diet exhibited elevated heart weight, enlarged cardiomyocytes, increase...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Hua, Yinan, Zhang, Yingmei, Dolence, Julia, Shi, Guo-Ping, Ren, Jun, Nair, Sreejayan
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554365/
https://ncbi.nlm.nih.gov/pubmed/23069627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0350
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!