Cargando...

Suppression of HIV-1 Infection by APOBEC3 Proteins in Primary Human CD4(+) T Cells Is Associated with Inhibition of Processive Reverse Transcription as Well as Excessive Cytidine Deamination

The Vif protein of human immunodeficiency virus type 1 (HIV-1) promotes viral replication by downregulation of the cell-encoded, antiviral APOBEC3 proteins. These proteins exert their suppressive effects through the inhibition of viral reverse transcription as well as the induction of cytidine deami...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Gillick, Kieran, Pollpeter, Darja, Phalora, Prabhjeet, Kim, Eun-Young, Wolinsky, Steven M., Malim, Michael H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554184/
https://ncbi.nlm.nih.gov/pubmed/23152537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02587-12
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!