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APOBEC3 Inhibition of Mouse Mammary Tumor Virus Infection: the Role of Cytidine Deamination versus Inhibition of Reverse Transcription

The apolipoprotein B editing complex 3 (APOBEC3) family of proteins is a group of intrinsic antiviral factors active against a number of retroviral pathogens, including HIV in humans and mouse mammary tumor virus (MMTV) in mice. APOBEC3 restricts its viral targets through cytidine deamination of vir...

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Detalhes bibliográficos
Main Authors: MacMillan, Alyssa L., Kohli, Rahul M., Ross, Susan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624289/
https://ncbi.nlm.nih.gov/pubmed/23449789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00112-13
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