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Antiviral Potency of APOBEC Proteins Does Not Correlate with Cytidine Deamination

The human cytidine deaminases APOBEC3G (hA3G) and APOBEC3F (hA3F) are intracellular antiretroviral factors that can hypermutate nascent reverse transcripts and inhibit the replication of human immunodeficiency virus type 1 (HIV-1). Both enzymes have two cytidine deaminase motifs, although only the C...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bishop, Kate N., Holmes, Rebecca K., Malim, Michael H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563846/
https://ncbi.nlm.nih.gov/pubmed/16912295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00839-06
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