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Antiviral Potency of APOBEC Proteins Does Not Correlate with Cytidine Deamination
The human cytidine deaminases APOBEC3G (hA3G) and APOBEC3F (hA3F) are intracellular antiretroviral factors that can hypermutate nascent reverse transcripts and inhibit the replication of human immunodeficiency virus type 1 (HIV-1). Both enzymes have two cytidine deaminase motifs, although only the C...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1563846/ https://ncbi.nlm.nih.gov/pubmed/16912295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00839-06 |
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