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Cleavage of Interferon Regulatory Factor 7 by Enterovirus 71 3C Suppresses Cellular Responses

Enterovirus 71 (EV71) is a positive-stranded RNA virus which is capable of inhibiting innate immunity. Among virus-encoded proteins, the 3C protein compromises the type I interferon (IFN-I) response mediated by retinoid acid-inducible gene-I (RIG-I) or Toll-like receptor 3 that activates interferon...

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Detalhes bibliográficos
Main Authors: Lei, Xiaobo, Xiao, Xia, Xue, Qinghua, Jin, Qi, He, Bin, Wang, Jianwei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554134/
https://ncbi.nlm.nih.gov/pubmed/23175366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01855-12
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