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Cleavage of the Adaptor Protein TRIF by Enterovirus 71 3C Inhibits Antiviral Responses Mediated by Toll-Like Receptor 3

Enterovirus 71 (EV71) causes hand-foot-and-mouth disease and neurological complications in young children. Although the underlying mechanisms remain obscure, impaired or aberrant immunity is thought to play a role. In infected cells, EV71 suppresses type I interferon responses mediated by retinoid a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lei, Xiaobo, Sun, Zhenmin, Liu, Xinlei, Jin, Qi, He, Bin, Wang, Jianwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165803/
https://ncbi.nlm.nih.gov/pubmed/21697485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00447-11
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