The 3C Protein of Enterovirus 71 Inhibits Retinoid Acid-Inducible Gene I-Mediated Interferon Regulatory Factor 3 Activation and Type I Interferon Responses

Enterovirus 71 (EV71) is a human pathogen that induces hand, foot, and mouth disease and fatal neurological diseases. Immature or impaired immunity is thought to associate with increased morbidity and mortality. In a murine model, EV71 does not facilitate the production of type I interferon (IFN) th...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Lei, Xiaobo, Liu, Xinlei, Ma, Yijie, Sun, Zhenmin, Yang, Yaowu, Jin, Qi, He, Bin, Wang, Jianwei
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
Sujets:
Virus-Cell Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916543/
https://ncbi.nlm.nih.gov/pubmed/20519382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02491-09
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