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Enterovirus 71 Inhibits Pyroptosis through Cleavage of Gasdermin D

Enterovirus 71 (EV71) can cause hand-foot-and-mouth disease (HFMD) in young children. Severe infection with EV71 can lead to neurological complications and even death. However, the molecular basis of viral pathogenesis remains poorly understood. Here, we report that EV71 induces degradation of gasde...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Lei, Xiaobo, Zhang, Zhenzhen, Xiao, Xia, Qi, Jianli, He, Bin, Wang, Jianwei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571240/
https://ncbi.nlm.nih.gov/pubmed/28679757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01069-17
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