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Rad51 Paralog Complexes BCDX2 and CX3 Act at Different Stages in the BRCA1-BRCA2-Dependent Homologous Recombination Pathway

The Rad51 paralogs are required for homologous recombination (HR) and the maintenance of genomic stability. The molecular mechanisms by which the five vertebrate Rad51 paralogs regulate HR and genomic integrity remain unclear. The Rad51 paralogs associate with one another in two distinct complexes:...

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Bibliographic Details
Main Authors: Chun, Jarin, Buechelmaier, Erika S., Powell, Simon N.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554112/
https://ncbi.nlm.nih.gov/pubmed/23149936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00465-12
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