Novel Smad proteins localize to IR-induced double-strand breaks: interplay between TGFβ and ATM pathways

Cellular damage from ionizing radiation (IR) is in part due to DNA damage and reactive oxygen species, which activate DNA damage response (DDR) and cytokine signaling pathways, including the ataxia telangiectasia mutated (ATM) and transforming growth factor (TGF)β/Smad pathways. Using classic double...

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Detalhes bibliográficos
Main Authors: Wang, Minli, Saha, Janapriya, Hada, Megumi, Anderson, Jennifer A., Pluth, Janice M., O’Neill, Peter, Cucinotta, Francis A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553971/
https://ncbi.nlm.nih.gov/pubmed/23221633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1038
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