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Selection of tRNA charging quality control mechanisms that increase mistranslation of the genetic code

Mistranslation can follow two events during protein synthesis: production of non-cognate amino acid:transfer RNA (tRNA) pairs by aminoacyl-tRNA synthetases (aaRSs) and inaccurate selection of aminoacyl-tRNAs by the ribosome. Many aaRSs actively edit non-cognate amino acids, but editing mechanisms ar...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yadavalli, Srujana S., Ibba, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553970/
https://ncbi.nlm.nih.gov/pubmed/23222133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1240
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