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Trypanosome CNOT10 is essential for the integrity of the NOT deadenylase complex and for degradation of many mRNAs
The degradation of most eukaryotic mRNAs is initiated by removal of the poly(A) tail, and the major deadenylase activity is associated with the CCR4/CAF1/NOT complex (NOT complex). We here study the role of CNOT10, a protein that is found in human and trypanosome, but not in yeast, NOT complexes. Tr...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3553956/ https://ncbi.nlm.nih.gov/pubmed/23221646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1133 |
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