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Vancomycin Treatment's Association with Delayed Intestinal Tissue Injury, Clostridial Overgrowth, and Recurrence of Clostridium difficile Infection in Mice

Antibiotic treatment, including vancomycin, for Clostridium difficile infection (CDI) has been associated with recurrence of disease in up to 25% of infected persons. This study investigated the effects of vancomycin on the clinical outcomes, intestinal histopathology, and anaerobic community during...

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Autors principals: Warren, Cirle A., van Opstal, Edward J., Riggins, Mary S., Li, Yuesheng, Moore, John H., Kolling, Glynis L., Guerrant, Richard L., Hoffman, Paul S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553708/
https://ncbi.nlm.nih.gov/pubmed/23147742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00877-12
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