Amixicile, a Novel Inhibitor of Pyruvate:Ferredoxin Oxidoreductase, Shows Efficacy against Clostridium difficile in a Mouse Infection Model

Clostridium difficile infection (CDI) is a serious diarrheal disease that often develops following prior antibiotic usage. One of the major problems with current therapies (oral vancomycin and metronidazole) is the high rate of recurrence. Nitazoxanide (NTZ), an inhibitor of pyruvate:ferredoxin oxid...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Warren, Cirle A., van Opstal, Edward, Ballard, T. Eric, Kennedy, Andrew, Wang, Xia, Riggins, Mary, Olekhnovich, Igor, Warthan, Michelle, Kolling, Glynis L., Guerrant, Richard L., Macdonald, Timothy L., Hoffman, Paul S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2012
Pynciau:
Experimental Therapeutics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421617/
https://ncbi.nlm.nih.gov/pubmed/22585229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00360-12
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