Amixicile, a Novel Inhibitor of Pyruvate:Ferredoxin Oxidoreductase, Shows Efficacy against Clostridium difficile in a Mouse Infection Model

Clostridium difficile infection (CDI) is a serious diarrheal disease that often develops following prior antibiotic usage. One of the major problems with current therapies (oral vancomycin and metronidazole) is the high rate of recurrence. Nitazoxanide (NTZ), an inhibitor of pyruvate:ferredoxin oxid...

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Detaylı Bibliyografya
Asıl Yazarlar: Warren, Cirle A., van Opstal, Edward, Ballard, T. Eric, Kennedy, Andrew, Wang, Xia, Riggins, Mary, Olekhnovich, Igor, Warthan, Michelle, Kolling, Glynis L., Guerrant, Richard L., Macdonald, Timothy L., Hoffman, Paul S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2012
Konular:
Experimental Therapeutics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421617/
https://ncbi.nlm.nih.gov/pubmed/22585229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00360-12
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