Vancomycin Treatment's Association with Delayed Intestinal Tissue Injury, Clostridial Overgrowth, and Recurrence of Clostridium difficile Infection in Mice

Antibiotic treatment, including vancomycin, for Clostridium difficile infection (CDI) has been associated with recurrence of disease in up to 25% of infected persons. This study investigated the effects of vancomycin on the clinical outcomes, intestinal histopathology, and anaerobic community during...

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Bibliographic Details
Main Authors: Warren, Cirle A., van Opstal, Edward J., Riggins, Mary S., Li, Yuesheng, Moore, John H., Kolling, Glynis L., Guerrant, Richard L., Hoffman, Paul S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553708/
https://ncbi.nlm.nih.gov/pubmed/23147742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00877-12
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