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A phase I/II, non-randomized, feasibility/safety and efficacy study of the combination of everolimus, cetuximab and capecitabine in patients with advanced pancreatic cancer

Background Improvements in knowledge of molecular mechanisms in cancer are the basis for new studies combining chemotherapy with targeted drugs. Inhibition of the epidermal growth factor receptor (EGFR) by erlotinib or cetuximab has limited or no activity, respectively, in pancreatic cancer. The cro...

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書誌詳細
主要な著者: Kordes, Sil, Richel, Dick J., Klümpen, Heinz-Josef, Weterman, Mariëtte J., Stevens, Arnoldus J. W. M., Wilmink, Johanna W.
フォーマット: Artigo
言語:Inglês
出版事項: Springer US 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553409/
https://ncbi.nlm.nih.gov/pubmed/22367239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-012-9802-1
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