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Phase II study of capecitabine and the oral mTOR inhibitor everolimus in patients with advanced pancreatic cancer

PURPOSE: The combination of an mTOR inhibitor with 5-fluorouracil-based anticancer therapy is attractive because of preclinical evidence of synergy between these drugs. According to our phase I study, the combination of capecitabine and everolimus is safe and feasible, with potential activity in pan...

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Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: Kordes, S., Klümpen, H. J., Weterman, M. J., Schellens, J. H. M., Richel, D. J., Wilmink, J. W.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441736/
https://ncbi.nlm.nih.gov/pubmed/25822310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-015-2730-y
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