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A phase I/II, non-randomized, feasibility/safety and efficacy study of the combination of everolimus, cetuximab and capecitabine in patients with advanced pancreatic cancer

Background Improvements in knowledge of molecular mechanisms in cancer are the basis for new studies combining chemotherapy with targeted drugs. Inhibition of the epidermal growth factor receptor (EGFR) by erlotinib or cetuximab has limited or no activity, respectively, in pancreatic cancer. The cro...

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Detalhes bibliográficos
Main Authors: Kordes, Sil, Richel, Dick J., Klümpen, Heinz-Josef, Weterman, Mariëtte J., Stevens, Arnoldus J. W. M., Wilmink, Johanna W.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553409/
https://ncbi.nlm.nih.gov/pubmed/22367239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-012-9802-1
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